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574 Down-Regulation of Sulf1 By Hypermethylation Mediates Resistance of Hepatocellular Carcinoma Cells to Chemotherapy-Induced Apoptosis

✍ Scribed by Shire, Abdirashid M.; Lai, Jinping; Zou, Hongzhi; Aderca, Ileana; Moser, Catherine D.; Jenkins, Robert B.; Roberts, Lewis R.


Book ID
122088054
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
228 KB
Volume
134
Category
Article
ISSN
0016-5085

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## Abstract ## BACKGROUND Previous reports indicate that Genistein, a naturally occurring isoflavonoid, exhibits strong antiangiogenic activity. The underlying mechanism of inhibition, however, remains unclear. Among the biologic effects of Genistein are the inhibition of tyrosine kinases and the