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570 Involvement of p53 in DNA strand break-induced apoptosis in postmitotic CNS neurons

✍ Scribed by Hiroshi Hatanaka; Yasushi Enokido

Book ID
117414064
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
145 KB
Volume
17
Category
Article
ISSN
0197-4580

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Apoptosis occurs not only in mitotic cells but also in postmitotic neuronal cells. We previously suggested that the tumor suppressor gene p53 is required for DNA strand break-induced apoptosis in dissociated culture of cerebellar granule neurons. In this study, we examined the role of p53 in apoptos