563: In vitro culture of trophoblasts isolated from maternal circulation: A potential non-invasive approach to prenatal diagnosis

Novel approaches to manipulating foetal

Novel approaches to manipulating foetal cells in the maternal circulation for non-invasive prenatal diagnosis of the unborn child

✍ Zhouwei Huang; Chui-Yee Fong; Kalamegam Gauthaman; Ponnusamy Sukumar; Mahesh Cho 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 304 KB

Due to the risks to the foetus with invasive prenatal diagnosis, non-invasive prenatal diagnosis (NIPD) is gaining tremendous interest but no reliable method that can be widely used has been developed to date. Manipulation of foetal cells and foetal cell-free genetic material in the maternal blood a