561 A comparative study to the effects of cetirizine terfenadine and triprolidine on actual driving and psychomotor performance
โ Scribed by VOLKERTS, E; VANWILLIGENBURG, A; VANLAAR, M; MAES, R
- Book ID
- 119060743
- Publisher
- Elsevier Science
- Year
- 1991
- Tongue
- English
- Weight
- 160 KB
- Volume
- 87
- Category
- Article
- ISSN
- 1097-6825
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Eighteen healthy volunteers received mizolastine 5 mg, 15 mg or 45 mg, terfenadine 60 mg, triprolidine 10 mg or placebo in a 6-way crossover, double blind study. Following each dose, subjects performed a series of tests of cognitive function and psychomotor performance at 1, 3, 5, 8 and 24 hours pos
Allergic cutaneous challenge causes mast cell and basophil mediator release which recruit inflammatory cells to the site of antigen administration. This secondary cell infiltration and mediator release is responsible for the changes seen during the late phase of allergic diseases. In this randomised