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55 Identifying Acetaminophen (APAP) Toxicity Amongst Indeterminate Cause of Acute Liver Failure (Alf)

โœ Scribed by Khandelwal, Niraj; James, Laura P.; Simpson, Pippa M.; Davern, Timothy J.; Roberts, Dean W.; Lee, William M.


Book ID
122712935
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
77 KB
Volume
134
Category
Article
ISSN
0016-5085

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Unrecognized acetaminophen toxicity as a
โœ Niraj Khandelwal; Laura P. James; Corron Sanders; Anne M. Larson; William M. Lee ๐Ÿ“‚ Article ๐Ÿ“… 2011 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 158 KB ๐Ÿ‘ 2 views

Despite extensive investigations, the cause of liver injury in 14% of patients with acute liver failure remains unknown (indeterminate). In a pilot study using a novel assay, highly specific acetaminophen-cysteine adducts were detected in 7 of 36 indeterminate patients (19%). To extend these observa