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55 Genetic polymorphisms in promoter region of osteopontin gene as a marker to determine hepatitis activity in patients with chronic hepatitis C

✍ Scribed by Atsushi Matsui; Satoshi Mochida; Masashi Naito; Mie Inao; Sumik Nagoshi; Michie Hashimoto; Shunji Mishiro; Kenji Fujiwara

Book ID: 119529964
Publisher: John Wiley and Sons
Year: 2003
Tongue: English
Weight: 126 KB
Volume: 38
Category: Article
ISSN: 0270-9139
DOI: 10.1016/s0270-9139(03)80098-8

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## Abstract It has been reported that genetic polymorphisms near the __IL28B__ gene or amino acid substitutions in hepatitis C virus (HCV) core protein are associated with the clinical outcome of peginterferon (PEG‐IFN) and ribavirin combination therapy. The impact of these factors on the pure sens