542 Tumour stem cells in oncogenic RAS-dependent rhabdomyosarcoma
β Scribed by G. Schaaf; F. Sage; A. Chan; F. Chen; M. Hamdi; D. Zwijnenburg; S. Boutet; M. Kool; T. Rando
- Book ID
- 119602323
- Publisher
- Elsevier Science
- Year
- 2010
- Tongue
- English
- Weight
- 45 KB
- Volume
- 8
- Category
- Article
- ISSN
- 1359-6349
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract An increasing body of evidence suggests that tumors might originate from a few transformed cells that share many properties with normal stem cells. However, it remains unclear how normal stem cells are transformed into cancer stem cells (CSCs). Here, we demonstrated that mutations causi
## Abstract Maintenance of Eβcadherin mediated cellβcell contacts is often required for the survival of epithelial cells and tissues. Here we report that oncogenic activation of HβRas in murine keratinocytes can prevent cell death induced by immunological disruption of Eβcadherin adhesion. A simila