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5.4. Analysis of linkage disequilibrium between the loci HLA-A, B and C

✍ Scribed by H. Arnold; B.D. Kiekebusch-Müller; W.R. Mayr

Book ID
113368758
Publisher
Elsevier Science
Year
1979
Tongue
English
Weight
82 KB
Volume
14
Category
Article
ISSN
0379-0738

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Haplotype analysis of the linkage group
Haplotype analysis of the linkage group HLA-A:HLA-B:Bf and its bearing on the interpretation of the linkage disequilibrium
✍ K. Bender; A. Mayerová; R. Frank; C. Hiller; T. Wienker 📂 Article 📅 1977 🏛 Springer 🌐 English ⚖ 275 KB

The analysis of 650 HLA-A:HAL-B:Bf three-factor haplotypes revealed significant associations only between alleles of the very closely linked genes HLA-A and HLA-B, and Bf, respectively. Most striking is the highly significnat association of the rare Bf variant F1 with HLA-B18 and of S1 with HLA-B13,