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537 - A phase II study of topotecan given as a continuous 21-day infusion every 28 days in platinum pre-treated ovarian carcinoma

✍ Scribed by S. Johnson; L. Pyle; K. King; M. Gore


Book ID
117664785
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
261 KB
Volume
33
Category
Article
ISSN
0959-8049

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## Abstract ## BACKGROUND Topotecan, administeredintravenously at a dose of 1.5 mg/m^2^ per day for 5 days every 21 days, is an established regimen in the treatment of recurrent ovarian carcinoma. Alternate dosing strategies have sought to improve toxicity. The authors evaluated the tolerability a