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533 FREQUENT INACTIVATION OF THE PAKT PATHWAY GENES IN NONSEMINOMATOUS GERM CELL TUMORS

โœ Scribed by A.S. Merseburger; J. Hennenlotter; U. Vogel; C. Springer; A.G. Anastasiadis; J.T. Hartmann; A. Stenzl; M.A. Kuczyk


Book ID
119617863
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
340 KB
Volume
6
Category
Article
ISSN
1569-9056

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Rodent models of pituitary tumorigenesis have implicated the retinoblastoma (Rb) pathway in the development of pituitary tumors. Previously, we reported that loss of p16 expression rather than loss of Rb occurs in most human pituitary adenomas. This alteration in these tumors is not associated with