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532 Differentiation of SYSY cells: Effect on phosphorylation and biological activity of tau

✍ Scribed by N. Haque; T. Tanaka; K. Iqbal; I. Grundke-Iqbal

Book ID: 118578087
Publisher: Elsevier Science
Year: 1996
Tongue: English
Weight: 280 KB
Volume: 17
Category: Article
ISSN: 0197-4580
DOI: 10.1016/s0197-4580(96)80534-3

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## Abstract A hallmark of several neurodegenerative disorders, including Alzheimer's disease and tauopathies, is the hyperphosphorylation of the microtubule‐associated protein tau. Tau phosphorylation by proline‐directed and non‐proline‐directed protein kinases has been tested using antibodies PHF1