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531 MICRORNA-198, DOWNREGULATED IN HEPATO- CELLULAR CARCINOMA, INHIBITS CELL GROWTH OF HEPATOCELLULAR CARCINOMA CELLS

✍ Scribed by N. Elfimova; A. Noetel; S. Schievenbusch; F. Schulze; H. Varnholt; M. Kwiecinski; M. Quasdorff; H.P. Dienes; M. Odenthal

Book ID
117377540
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
50 KB
Volume
50
Category
Article
ISSN
0168-8278

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## Abstract We studied __in vitro__ effects of glycogen synthase kinase 3Ξ² (GSK3Ξ²)‐inhibitor lithium on the growth of hepatocellular carcinoma (HCC) cells. Lithium induced strong growth inhibition (>70%) in 75% (__n__ = 9 of 12) of cell lines, apparently independent from the status of major genes t