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520 Regulation of G protein-mediated signal transduction by cytoskeletal elements in Alzheimer's disease brain

✍ Scribed by H. Ozawa; M. Yamamoto; T. Saito; E. Hashimoto; S. Hatta; L. Frölich; P. Riederer; H. Ohshika; N. Takahata


Book ID
117414038
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
200 KB
Volume
17
Category
Article
ISSN
0197-4580

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## Abstract We report the effects of amyloid precursor protein (APP) fragment 714–723 (APP~714–723~; peptide P1) and its V717F and V717G mutants (peptides P2 and P3, respectively) on G‐protein activity ([^35^S]GTPγS binding) in membranes from postmortem human control and Alzheimer's disease (AD) br