Diastereospecific synthesis of ketooxind
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Peng Yu; James M Cook
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Article
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1997
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Elsevier Science
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French
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A convenient method has been developed to convert Na-H tetracyclicketone la into the two corresponding oxindoles[C(7)l diastereospecifically. Treatment of the Na-H, Nb-benzyl tetracyclicketone la with t-BuOCl provided diastereomer 2a (related to Voacanga oxindoles), whereas the same process with Nb-