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5115099 Substrates for determination of enzyme activity and intermediates for synthesis of the substrates as well as process for producing the intermediates


Book ID
123374931
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
69 KB
Volume
10
Category
Article
ISSN
0734-9750

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A convenient method has been developed to convert Na-H tetracyclicketone la into the two corresponding oxindoles[C(7)l diastereospecifically. Treatment of the Na-H, Nb-benzyl tetracyclicketone la with t-BuOCl provided diastereomer 2a (related to Voacanga oxindoles), whereas the same process with Nb-