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5,10-seco-steroids, a new type of steroid derivatives containing a ten-membered ring

✍ Scribed by M.Lj. Mihailović; M. Stefanović; Lj. Lorenc; M. Gašić


Publisher
Elsevier Science
Year
1964
Tongue
French
Weight
183 KB
Volume
5
Category
Article
ISSN
0040-4039

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5,lO-Seco-steroida containing a ten-membered ring (2) (instead of the two fused six-membered rings A and B) (e.g. I and II on Scheme 1) represent a suitable eubetrate for the study of truuunmilar reactivity in a medim-aired ring sytatem, because of the rel&ive rigidity of the general steroid framewo

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Dedicated to Dr. Gunther OhlofTon the occasion of his 65th birthday (7.11.89) Thermolysis of steroidal 5~,8a~peroxides of type 3a-d generates as major products the corresponding diseco compounds containing a 14-membered ring instead of the standard A-B-C-ring skeleton. Depending on the reaction cond