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5.1 Therapeutic Potential and Challenges of Targeting Receptor Tyrosine Kinase ROR1 with Monoclonal Antibodies in CLL

✍ Scribed by Jiahui Yang; Sivasubramanian Baskar; Ka Yin Kwong; Michael G. Kennedy; Adrian Wiestner; Christoph Rader


Book ID
119218947
Publisher
Elsevier
Year
2011
Tongue
English
Weight
148 KB
Volume
11
Category
Article
ISSN
2152-2650

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Congenital insensitivity to pain with anhidrosis (CIPA), also called hereditary sensory and autonomic neuropathy type IV (HSAN IV), is caused by mutations of the NTRK1 gene coding for the neurotrophic tyrosine kinase receptor type 1. We report the results of the NTRK1 sequence analysis in a CIPA fam