508 APPLICABILITY AND USEFULNESS OF “CONDITIONED” CHONDROCYTES IN THREE-DIMENSIONAL IN VITRO ARTHRITIS MODELS
✍ Scribed by M.F. Rai; A. Hauser; T. Graeve; M.F. Schmidt
- Book ID
- 114351718
- Publisher
- Elsevier Science
- Year
- 2009
- Tongue
- English
- Weight
- 42 KB
- Volume
- 17
- Category
- Article
- ISSN
- 1063-4584
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Sheep articular chondrocytes were cultured for 3, 6, and 9 weeks on a three-dimensional porous scaffold from poly(L/DL-lactide) 80/20%. Cell growth and activity was estimated from the amount of proteoglycans attached to the polylactide scaffold and the amounts of DNA and proteins measured in the cel
## Abstract The promising potential of a RAD‐16 self‐assembly‐peptide hydrogel as a scaffold for tissue‐engineered cartilage was investigated. Within 3 weeks of in vitro culture, chondrocytes within the hydrogel produced a high amount of GAG and type‐II collagen, which are the components of cartila