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501: Strategies for population-wide genetic carrier screening: a cost-effectiveness analysis

✍ Scribed by Weisinger, Rebecca; Hawthorne, Felicia; Sheikh, Mona; Wong, Kenny; Evans, Eric; Haque, Imran; Pyeritz, Reed; Srinivasan, Ramji

Book ID
122147863
Publisher
Elsevier Science
Year
2014
Tongue
English
Weight
229 KB
Volume
210
Category
Article
ISSN
1097-6868

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## Background: It has been estimated that the prevalence of carriers of a mutated mismatch repair (mmr) gene among the general population in western countries is between 5 and 50 per 10,000. these carriers have a risk of >85% of developing colorectal carcinoma (crc) and therefore need careful follo