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500-Picosecond molecular dynamics in water of the Man.alpha.1 .fwdarw. 2Man.alpha. glycosidic linkage present in Asn-linked oligomannose-type structures on glycoproteins

โœ Scribed by Edge, C. J.; Singh, U. C.; Bazzo, R.; Taylor, G. L.; Dwek, R. A.; Rademacher, Thomas W.

Book ID
127115429
Publisher
American Chemical Society
Year
1990
Tongue
English
Weight
453 KB
Volume
29
Category
Article
ISSN
0006-2960

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500-Picosecond molecular dynamics in wat
500-Picosecond molecular dynamics in water of the Man.alpha.1 .fwdarw. 2Man.alpha. glycosidic linkage present in Asn-linked oligomannose-type structures on glycoproteins
โœ Edge, C. J.; Singh, U. C.; Bazzo, R.; Taylor, G. L.; Dwek, R. A.; Rademacher, Th ๐Ÿ“‚ Article ๐Ÿ“… 1990 ๐Ÿ› American Chemical Society ๐ŸŒ English โš– 453 KB

Molecular dynamics simulations of the M a n a 1-2Mana glycosidic linkage found in the N-linked glycans of glycoproteins were performed in vacuo and in the presence of water. In the latter case significant dampening of the molecular fluctuations was found when compared to the in vacuo simulation. A 5