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50 Single-molecule studies of human telomeric G-quadruplexes and the effect of oxidative damage

✍ Scribed by Fleming, Aaron M.; An, Na; Burrows, Cynthia J.


Book ID
127219997
Publisher
Adenine Press
Year
2013
Tongue
English
Weight
136 KB
Volume
31
Category
Article
ISSN
0739-1102

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Here we report that human telomere guanine-rich sequence AGGG(TTAGGG) 3 (G4) and hemin can form a G-quadruplex-hemin complex (GHC) which exhibits good electrochemical characteristics. The redox signals of the complex and the electrocatalytic activities toward the reduction of hydrogen peroxide have