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50 Predictive value of p53, C-erbB-2 and VEGF expression on adjuvant chemotherapy in NSCLC

✍ Scribed by Wu, Yi-Iong; Yu, Hui

Book ID: 123365816
Publisher: Elsevier Science
Year: 2003
Tongue: English
Weight: 344 KB
Volume: 41
Category: Article
ISSN: 0169-5002
DOI: 10.1016/S0169-5002(03)92741-3

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## Abstract ## Background and Objectives p53 tumor suppressor gene has a dual role as a trigger of apoptosis and as an initiator of DNA repair. The Bcl‐2 can work to protect cells from apoptosis, which is induced by p53 gene. These facts suggest the significant role of these genes in the genesis a