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5-Hydroxytryptamine produces presynaptic facilitation of cholinergic transmission in rabbit parasympathetic ganglia

✍ Scribed by Toshihiko Nishimura; Takashi Akasu


Book ID
119096950
Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
752 KB
Volume
26
Category
Article
ISSN
0165-1838

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Intracellular recordings were made from neurons of vesical parasympathetic ganglia (VPG) isolated from the rabbit urinary bladder and maintained, in vitro. Bath-application of norepinephrine (NE, 500 nM-5 pM) caused a hyperpolarizing response at the postsynaptic membrane of VPG neurons in a concent