✦ LIBER ✦

5-Hydroxytryptamine in frog's skin

✍ Scribed by John H. Welsh; Joyce B. Zipf

Publisher: John Wiley and Sons
Year: 1966
Tongue: English
Weight: 891 KB
Volume: 68
Category: Article
ISSN: 0021-9541
DOI: 10.1002/jcp.1040680105

No coin nor oath required. For personal study only.

✦ Synopsis

The amounts of 5-hydroxytryptamine (5-HT) in the skin of nine species 01 anurans were estimated by the fluorescence method. Relatively large quantities of 5-HT were found in the dorsal skin of five species of semi-terrestrial frogs, while in the skins of four highly aquatic species none, or only a trace, was found. Using the histochemical fluorescence method of Falck, 5-HT was located in the granules of the venom glands of Rana pipiens, a semi-terrestrial species, while no fluorescing glands were found in R. catesbeiawa, a highly aquatic species. The results of Erspamer and others are discussed. It is suggested that the most probable role of 5-HT in frog skin is that of defense against land predators.

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