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5-HT3 receptors antagonists block morphine- and nicotine- but not amphetamine-induced place-preference conditioning

โœ Scribed by Acquas, E.; Carboni, E.; Leone, P.; Di Chiara, G.

Book ID
114076045
Publisher
Elsevier Science
Year
1988
Weight
89 KB
Volume
20
Category
Article
ISSN
0031-6989

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5HT3receptor antagonists block morphine-
5HT3receptor antagonists block morphine- and nicotine-but not amphetamine-induced reward
โœ E. Carboni; E. Acquas; P. Leone; G. Chiara ๐Ÿ“‚ Article ๐Ÿ“… 1989 ๐Ÿ› Springer ๐ŸŒ English โš– 384 KB

The effect of two potent and specific antagonists of 5HT3 receptors, ICS 205-930 and MDL 72222, on the reinforcing properties of amphetamine, morphine and nicotine was studied in rats. Durg-induced reinforcement was assessed by measuring drug-conditioned place preference. ICS 205-930 and MDL 72222 d