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5-HT3- and 5-HT2C-antagonist properties of cyamemazine: significance for its clinical anxiolytic activity

✍ Scribed by M. Alvarez-Guerra; F. d’Alché-Birée; W. A. Wolf; F. Vargas; M. Dib; R. P. Garay


Publisher
Springer
Year
2000
Tongue
English
Weight
73 KB
Volume
147
Category
Article
ISSN
0033-3158

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Herein, we evaluate the interaction of the ␣ 2 -AR antagonist, yohimbine, as compared to fluparoxan, at multiple monoaminergic receptors and examine their roles in the modulation of adrenergic, dopaminergic and serotonergic transmission in freelymoving rats. Yohimbine displays marked affinity at hum