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5-HT2 presynaptic receptors mediate inhibition of glutamate release from cerebellar mossy fibre terminals

✍ Scribed by Guido Maura; Roberta Carbone; Maddalena Guido; Mario Pestarino; Maurizio Raiteri

Book ID
115886834
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
730 KB
Volume
202
Category
Article
ISSN
0014-2999

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## Abstract Presynaptic 5‐HT~2A~ receptor modulation of glutamate release from rat cerebrocortical nerve terminals (synaptosomes) was investigated by using the 5‐HT~2A/2C~ receptor agonist (±)‐1‐[2,5‐dimethoxy‐4‐iodophenyl]‐2‐aminopropane (DOI). DOI potently inhibited 4‐aminopyridine (4AP)‐evoked g