๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

5-HT 3 Receptor Partial Agonist Modulation, a Novel Approach to the Treatment of Diarrhea Predominant Irritable Bowel Syndrome (IBS-D)

โœ Scribed by Manning, David ;Wierschke, Jonathan D. ;Barnes, Nicholas M. ;Moore, Nicholas


Book ID
122198013
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
133 KB
Volume
140
Category
Article
ISSN
0016-5085

No coin nor oath required. For personal study only.


๐Ÿ“œ SIMILAR VOLUMES


Novel serotonin type 3 receptor partial
โœ David D. Manning; Christopher L. Cioffi; Alexander Usyatinsky; Kevin Fitzpatrick ๐Ÿ“‚ Article ๐Ÿ“… 2011 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 474 KB

Serotonin type 3 (5-HT(3)) receptor partial agonists are being targeted as potential new drugs for the treatment of irritable bowel syndrome (IBS). Two new chemical series bearing indazole and indole cores have exhibited nanomolar binding affinity for the h5-HT(3)A receptor. A range of partial agoni