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5-HT 1A and 2A receptor positive cells in the cerebella of mice and human and their decline during aging

✍ Scribed by David T. Yew; Lai-Yin Yeung; Maria Sen-Mun Wai; Ying T. Mak

Publisher: John Wiley and Sons
Year: 2009
Tongue: English
Weight: 346 KB
Volume: 72
Category: Article
ISSN: 1059-910X
DOI: 10.1002/jemt.20717

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

This study evaluated the 5‐HT1A and 5‐HT2A receptor positive cells in the cerebella of mice and human by immunocytochemistry. Mice were of ages 1, 3, and 12 months whereas the human subjects were divided into two groups, a younger 57–78 years old group and an older 82–91 years old group. Both 5‐HT1A and 5‐HT2A receptor positive cells were observed in the molecular and granular layers of the cerebella of mice and human. Although there was a decline in these positive cells during aging, no regional difference in the positive cells were observed in the anterior, middle, and posterior regions of the cerebella. Microsc. Res. Tech. 2009. © 2009 Wiley‐Liss, Inc.

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