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5-Fluorouracil response in a large panel of colorectal cancer cell lines is associated with mismatch repair deficiency

✍ Scribed by Bracht, K; Nicholls, A M; Liu, Y; Bodmer, W F


Book ID
110000569
Publisher
Nature Publishing Group
Year
2010
Tongue
English
Weight
404 KB
Volume
103
Category
Article
ISSN
0007-0920

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Gamma-Interferon (IFN-y) and the antimetabolites 5fluorouracil(5-FU) and 5-fluoro-2'-deoxyuridine (FUdR) were investigated as individual agents and in combination for their in vitro antiproliferative capacity and for their effect on the expression of HLA class-I antigen, carcinoembryonic antigen (CE