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5-Fluorouracil and derivatives in cancer chemotherapy II: Possible in vivo formation and stabilization of 5-fluoro-2′-deoxyuridine

✍ Scribed by J. J. Windheuser; Johnson Jato

Publisher
John Wiley and Sons
Year
1972
Tongue
English
Weight
220 KB
Volume
61
Category
Article
ISSN
0022-3549

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Thymidine labeling index of human breast carcinoma: Enhancement of in vitro labeling by 5-fluorouracil and 5-fluoro-2′ - deoxyuridine
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Inhibitors of thymidylate synthetase, 5-fluoro-2'-deoxyuridine (FUDR) and 5fluorouracil (FU) , enhanced in uitm thymidine labeling of human breast carcinoma cells. Their use resulted in an increase in the measured thymidine labeling index (TLI) of breast carcinomas by increasing detectability of lab