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5-bromodeoxyuridine substitution and differential radiosensitivity of uni- and bi-filar chromatids

โœ Scribed by Mercy Jacob


Book ID
113254114
Publisher
Elsevier Science
Year
1982
Weight
190 KB
Volume
103
Category
Article
ISSN
0165-7992

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5-Bromodeoxyuridine (BrdU)-induced sister chromatid exchanges (SCEs) are mainly determined during replication on a BrdU-substituted template. The BrdU, once incorporated, is rapidly excised as uracil (U), and the gap is repaired with the incorporation of BrdU from the medium, which leads to further