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5-Azacytidine Modulates the Response of Sensitive and Multidrug-Resistant K562 Leukemic Cells to Cytostatic Drugs

✍ Scribed by Thomas Efferth; Bernard W. Futscher; Rainhardt Osieka

Book ID
115590152
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
323 KB
Volume
27
Category
Article
ISSN
1079-9796

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## Abstract Partially purified uridine kinases from 5‐azacytidine‐sensitive and ‐resistant leukemic cells of AKR mice were separated on a Sephadex G‐200 column. The elution profile of both enzymes was similar although specific activity of uridine kinase from 5‐azacytidine‐resistant cells was more t