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5-Aza-7-deazaguanine DNA: Recognition and Strand Orientation of Oligonucleotides Incorporating Anomeric Imidazo[1,2-a]-1,3,5-triazine Nucleosides

✍ Scribed by Frank Seela; Stefan Amberg; Alexander Melenewski; Helmut Rosemeyer


Publisher
John Wiley and Sons
Year
2001
Tongue
German
Weight
182 KB
Volume
84
Category
Article
ISSN
0018-019X

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2-Amino-8-(2-deoxy-2-fluoro-β-D-arabinof
✍ Virginie Glaçon; Frank Seela 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 German ⚖ 112 KB

## Abstract Nucleobase‐anion glycosylation of 2‐[(2‐methyl‐1‐oxopropyl)amino]imidazo[1,2‐__a__]‐1,3,5‐triazin‐4(8__H__)‐one (**6**) with 3,5‐di‐__O__‐benzoyl‐2‐deoxy‐2‐fluoro‐__α__‐D‐arabinofuranosyl bromide (**8**) furnishes a mixture of the benzoyl‐protected anomeric 2‐amino‐8‐(2‐deoxy‐2‐fluoro‐D