𝔖 Bobbio Scriptorium
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5 A role for mutant p53 in promoting invasion

✍ Scribed by K. Vousden; P. Muller; P. Caswell

Book ID
119601795
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
45 KB
Volume
8
Category
Article
ISSN
1359-6349

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✍ Xiao-Chun Zhang; Jian Chen; Chun-Hui Su; Heng-Yin Yang; Mong-Hong Lee πŸ“‚ Article πŸ“… 2008 πŸ› John Wiley and Sons 🌐 English βš– 386 KB

## Abstract The 5th subunit of COP9 signalosome (CSN5, also known as Jab1 or COPS5) is implicated in regulating p53 activity and is overexpressed in various tumors. However, the precise roles of CSN5 in p53 network and tumorigenesis are not well characterized. Here we show that CSN5 is a critical r