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5-(4-Fluoro-3-phenoxy­phen­yl)-3-phenyl-4,5-dihydro­isoxazole

✍ Scribed by Chopra, Deepak ;Mohan, T. P. ;Vishalakshi, B

Publisher
International Union of Crystallography
Year
2006
Tongue
English
Weight
186 KB
Volume
62
Category
Article
ISSN
1600-5368

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✦ Synopsis

The title compound, C 21 H 16 FNO 2 , is chiral, having an asymmetric C atom, and is found to crystallize in a noncentrosymmetric space group. The five-membered isoxazole ring exists in an envelope conformation. The crystal structure is stabilized by weak intermolecular C-HÁ Á ÁO interactions.

📜 SIMILAR VOLUMES

3-(4-Fluoro-3-phenoxy­phen­yl)-5-(4-meth
3-(4-Fluoro-3-phenoxy­phen­yl)-5-(4-methoxy­phen­yl)isoxazole
✍ Chopra, Deepak ;Mohan, T. P. ;Vishalakshi, B. 📂 Article 📅 2006 🏛 International Union of Crystallography 🌐 English ⚖ 192 KB

The crystal structure of the title compound, C~22~H~16~FNO~3~, is stablized by C—H...π intermolecular interactions.

4-[5-(4-Fluoro­phen­yl)-3-isopropyl­isox
4-[5-(4-Fluoro­phen­yl)-3-isopropyl­isoxazol-4-yl]pyridine
✍ Peifer, Christian ;Abadleh, Mohammed ;Schollmeyer, Dieter ;Laufer, Stefan 📂 Article 📅 2006 🏛 International Union of Crystallography 🌐 English ⚖ 240 KB

In the title compound, C 17 H 15 FN 2 O, the exocyclic bond angles at the C atoms of the isoxazole ring bearing the pyridyl and 4fluorophenyl substituents are 129.66 (17) and 134.58 ( 16) , respectively. The structure was determined in a study of the molecular geometry of isoxazole derivatives with

4-[3-(4-Fluoro­phen­yl)-5-isopropyl­isox
4-[3-(4-Fluoro­phen­yl)-5-isopropyl­isoxazol-4-yl]pyridine
✍ Peifer, Christian ;Abadleh, Mohammed ;Schollmeyer, Dieter ;Laufer, Stefan 📂 Article 📅 2006 🏛 International Union of Crystallography 🌐 English ⚖ 209 KB

Single-crystal X-ray study in main residue R factor = 0.066 wR factor = 0.198 Data-to-parameter ratio = 13.4 For details of how these key indicators were automatically derived from the article, see http://journals.iucr.org/e.

3-(4-Chloro­phen­yl)isoxazole-5-carbalde
3-(4-Chloro­phen­yl)isoxazole-5-carbaldehyde
✍ Zhang, Da-Tong ;Ma, Yi ;Shi, Nian-Qiu 📂 Article 📅 2006 🏛 International Union of Crystallography 🌐 English ⚖ 78 KB

Single-crystal X-ray study T = 298 K Mean (C-C) = 0.003 A R factor = 0.049 wR factor = 0.119 Data-to-parameter ratio = 12.7 For details of how these key indicators were automatically derived from the article, see http://journals.iucr.org/e.

4-[5-(4-Fluoro­phen­yl)-3-isopropyl­isox
4-[5-(4-Fluoro­phen­yl)-3-isopropyl­isoxazol-4-yl]pyridin-2(1H)-one
✍ Abadleh, Mohammed ;Peifer, Christian ;Kinkel, Katrin ;Schollmeyer, Dieter ;Laufe 📂 Article 📅 2007 🏛 International Union of Crystallography 🌐 English ⚖ 264 KB

The crystal structure of the title compound, C~17~H~15~FN~2~O~2~, was determined as part of a study of the biological activity of pyridine-substituted isoxazole derivatives as mitogen-activated protein kinase (MAPK) inhibitors. In the crystal structure of the title compound, the compound exists in t