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5-30-19 Clinical and paraclinical correlations in Huntington's disease

✍ Scribed by Roth, J.; Havrdová, E.; Židovská, J.; Ru̇žičková, S.; Línek, V.; Preiss, M.; Jech, R.; Ru̇žička, E.


Book ID
123064860
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
178 KB
Volume
150
Category
Article
ISSN
0022-510X

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## Abstract Huntington's disease (HD) is caused by an abnormally expanded CAG repeat in the __IT__‐__15__ gene, which encodes a widely expressed protein called huntingtin. Abnormalities of mitochondrial respiratory chain function, specifically complex II/III, have been identified in HD striatum and