The expression of Fhit protein is relate
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Zoran Gatalica; Subodh M. Lele; B. Alan Rampy; Brent A. Norris
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Article
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2000
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John Wiley and Sons
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English
⚖ 549 KB
## BACKGROUND. The FHIT gene, located at human chromosome 3p14.2, frequently is deleted in a number of human tumors, including breast carcinoma. Its protein product (Fhit) is presumed to have tumor suppressor function. Loss of expression of a tumor suppressor gene is an important step in tumor prog