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4E binding protein 1 expression is inversely correlated to the progression of gastrointestinal cancers

✍ Scribed by M.Elena Martı́n; M.Isabel Pérez; Clara Redondo; M.Isabel Álvarez; Matilde Salinas; Juan L Fando


Book ID
117755561
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
280 KB
Volume
32
Category
Article
ISSN
1357-2725

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The expression of Fhit protein is relate
✍ Zoran Gatalica; Subodh M. Lele; B. Alan Rampy; Brent A. Norris 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 549 KB

## BACKGROUND. The FHIT gene, located at human chromosome 3p14.2, frequently is deleted in a number of human tumors, including breast carcinoma. Its protein product (Fhit) is presumed to have tumor suppressor function. Loss of expression of a tumor suppressor gene is an important step in tumor prog