4D time-resolved magnetic resonance angiography for noninvasive assessment of pulmonary arteriovenous malformations patency
✍ Scribed by Loic Boussel; Alexandru Cernicanu; Liesbeth Geerts; Delphine Gamondes; Chahera Khouatra; Vincent Cottin; Didier Revel; Philippe Douek
- Publisher
- John Wiley and Sons
- Year
- 2010
- Tongue
- English
- Weight
- 305 KB
- Volume
- 32
- Category
- Article
- ISSN
- 1053-1807
No coin nor oath required. For personal study only.
✦ Synopsis
Purpose: To assess the capability of four-dimensional (4D) time-resolved magnetic resonance angiography (MRA) to assess pulmonary arteriovenous malformations (PAVMs) patency by analyzing pulmonary arterial and venous enhancement kinetics.
Materials and Methods: Seven patients with eight documented patent PAVMs underwent a 4D-MRA with keyhole and viewsharing compression at 3T with the following parameters: spatial resolution 0.87 Â 0.87 Â 1.4 mm 3 ; field of view 500 Â 350 Â 238 mm 3 ; dynamic scan time (temporal resolution) 1.2 seconds; total acquisition time 18.1 seconds for six dynamic datasets (6 Â 1.2 sec þ reference scan: 10.9 sec). All images were reviewed by two experienced radiologists. Image quality was rated on a qualitative 5-point scale (1: not assessable to 5: excellent). Signal value was measured on cross-sectional planes for the afferent arteries and efferent veins of the PAVM, and for normal reference healthy arteries and veins. The difference in time to peak for each coupled artery/vein (dTTPav) was calculated and compared with a Mann-Whitney test between PAVMs and reference vessels.
Results: Mean image quality was 3.2 6 0.9. dTTPav was significantly smaller in PAVMs (0.15 6 0.76 sec) than in reference vessels (3.75 6 1.62 sec), P < 0.001. Conclusion: 4D-MRA is a promising tool for noninvasive assessment of PAVM patency.