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499 Prox1 expression in liver metastases from colon carcinoma

✍ Scribed by A.R. Ceausu; S. Gurzu; P.N. Gaje; I. Jung; M. Raica; A.M. Cimpean

Book ID
119602280
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
66 KB
Volume
8
Category
Article
ISSN
1359-6349

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CD44 is a family of cell-surface adhesion molecules which exist in several isoforms arising from mRNA alternative. Malignant transformation of colonic mucosa is associated with alterations in CD44 expression, which result in up-regulation of high-molecular-weight CD44 isoforms and down-regulation of