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498 A T-CELL ASSOCIATED CYTOKINE, INTERLEUKIN-17, PROMOTES AN INFLAMMATORY PHENOTYPE IN DEGENERATIVE HUMAN INTERVERTEBRAL DISC CELLS

✍ Scribed by M.A. Gabr; L.A. Setton; S.M. Sinclair; L. Jing; C.R. Brown; W.J. Richardson; J. Chen

Book ID
114351708
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
96 KB
Volume
17
Category
Article
ISSN
1063-4584

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## Abstract Interleukin‐17 (IL‐17) is a cytokine recently shown to be elevated, along with interferon‐γ (IFNγ) and tumor necrosis factor (TNFα), in degenerated and herniated intervertebral disc (IVD) tissues, suggesting a role for these cytokines in intervertebral disc disease. The objective of our