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49 Proteomic analysis of the mechanism of action of a COX2 Inhibitor (DuP-697) in mesothelioma

โœ Scribed by Agarwal, V.; Hodgkinson, V.C.; Eagle, G.L.; Scaife, L.; Lind, M.J.; Cawkwell, L.


Book ID
118574722
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
83 KB
Volume
71
Category
Article
ISSN
0169-5002

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## Abstract Small molecule inhibitors of cyclinโ€dependent kinase 5 (CDK5) protect neurons from cell death following various insults. To elucidate the cellular mechanism of action we investigated changes in protein phosphorylation in cultured rat cerebellar granule neurons after administration of th