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49. Modulating Mitochondrial Base Excision Repair to Alter Cell Cycle Progression

✍ Scribed by Christopher Koczor; Inna Shokolenko; Glenn Wilson; Susan LeDoux


Book ID
116751845
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
47 KB
Volume
9
Category
Article
ISSN
1567-7249

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## Abstract Primary astrocyte cultures were used to investigate the modulation of DNA repair as a tool for sensitizing astrocytes to genotoxic agents. Base excision repair (BER) is the principal mechanism by which mammalian cells repair alkylation damage to DNA and involves the processing of relati