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487 Mapping Stem Cell Clones in Human Intestinal Crypts

โœ Scribed by Adam Humphries; Stuart A. McDonald; Paul J. Tadrous; Nicholas A. Wright


Book ID
119430210
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
108 KB
Volume
136
Category
Article
ISSN
0016-5085

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A generally accepted model for the origin of human cancer is that tumours arising from the gut-lining epithelium-the adenomas and carcinomas-are of clonal origin, i.e., they are derived from a single 'abnormal' cell. Recent work has shed considerable light on these matters and suggests that this mod