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4840899 Method for the production of ribavirin using high robose donor concentrations

✍ Scribed by Marchesini, G.; Bernardi, D.; Miccoli, R.; Rossi, E.; Vaccaro, O.; De Rosa, M.; Bonora, E.; Bruno, G.

Book ID: 122350213
Publisher: Elsevier Science
Year: 1989
Tongue: English
Weight: 71 KB
Volume: 7
Category: Article
ISSN: 0734-9750
DOI: 10.1016/0734-9750(89)90755-6

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A method for the measurement of erythrocyte 5-phosphoribosyl 1-pyrophosphate (PP-ribose-P) using HPLC is described. lnosinic acid formed from the enzyme-catalyzed reaction of hypoxanthine and PP-ribose-P using partially purified hypoxanthine-guanine phosphoribosyltransferase is measured after chroma