4751183 Monoclonal antibody that recognizes a structure common to human interleukin-2 (TCGF) and to the light lambda chain of human immunoglobulin and lines of hybridoma cells that produce these monoclonal antibodies

Selection and characterization of monocl

Selection and characterization of monoclonal antibodies to the idiotype-like structure of an interleukin-2-producing human leukemia t-cell line

✍ Alessandro Moretta; Giuseppe Pantaleo; Miguel Lopez-Botet; Lorenzo Moretta 📂 Article 📅 1985 🏛 John Wiley and Sons 🌐 French ⚖ 816 KB

## Abstract A variant of the Jurkat leukemia cell line termed JA3 (surface phenotype: T11 +, T3 +, T4‐, T8‐, T6‐, T1 +, 3A1 +, HLA‐DR‐, Tac‐, 4FZ+) has been used for mouse immunization and production of monoclonal antibodies (MAbs) to molecules carrying clonotypic determinants that are thought to s