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475 PROTEOMIC CHARACTERIZATION OF MOUSE CARTILAGE DEGRADATION IN VITRO

✍ Scribed by R. Wilson; D. Belluoccio; C. Little; A. Fosang; J. Bateman

Book ID: 114351101
Publisher: Elsevier Science
Year: 2008
Tongue: English
Weight: 278 KB
Volume: 16
Category: Article
ISSN: 1063-4584
DOI: 10.1016/s1063-4584(08)60515-4

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## Abstract Rheumatoid synovium in coculture with cartilage has been shown to release a factor(s) that stimulates the depletion of glycosaminoglycans (GAG) from cartilage matrix. Human rheumatoid synovium was enzymatically disaggregated and the isolated cells were subjected to a variety of mechanic