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47 Targeting Ptp4a3 in Colon Tumorigenesis and Cancer Progression

✍ Scribed by Zimmerman, M.W.; Homanics, G.E.; Lazo, J.S.


Book ID
122025790
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
55 KB
Volume
48
Category
Article
ISSN
0959-8049

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## Abstract Tristetraprolin (TTP) is an AU‐rich element‐binding protein that regulates mRNA stability. Here, we report that TTP suppress the growth of human colon cancer cells both __in vivo__ and __in vitro__ by regulating of the expression of vascular endothelial growth factor (VEGF). TTP protein