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447 SKP2 OVEREXPRESSION AND CYTOPLASMIC P27KIP1 IMMUNOREACTIVITY ARE PREDICTORS OF POOR PROGNOSIS IN PATIENTS WITH EXTRAHEPATIC BILE DUCT CANCER

โœ Scribed by Y.H. Baek; H.J. Kim; J.H. Park; D.I. Park; Y.K. Cho; C.I. Sohn; W.K. Jeon; B.I. Kim; M.K. Kim; D.H. Kim; J.H. Sohn


Book ID
117376373
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
64 KB
Volume
48
Category
Article
ISSN
0168-8278

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This study was undertaken to identify potential abnormalities of p27 Kip1 and cyclin D1 expression in extrahepatic bile duct carcinomas and to assess the prognostic significance of p27 Kip1 and cyclin D1 levels for patients with this disease. Decreased p27 Kip1 expression (F50% nuclei staining) and