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445 The pharmacokinetics (PK) and safety of a single dose of adefovir dipivoxil (ADV) in children and adolescents (aged 2–17) with chronic hepatitis B

✍ Scribed by E. Sokal; D. Kelly; S. Wirth; J. Mizerski; B. Lu; K. Kleber; J. Shah; G. Currie; C.L. Brosgart

Book ID
117373274
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
63 KB
Volume
40
Category
Article
ISSN
0168-8278

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✍ Maureen M. Jonas; Deirdre Kelly; Henry Pollack; Jacek Mizerski; Jeff Sorbel; Dav 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 209 KB 👁 1 views

This study investigated the efficacy, safety, and pharmacokinetics of adefovir dipivoxil (ADV) in children and adolescents with chronic hepatitis B (CHB). A total of 173 treatmentnaive and treatment-experienced children with hepatitis B e antigen (HBeAg)؉ CHB were randomized to ADV or placebo. Rando