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442 ACTIVITY AND EXPRESSION OF HYALURONIDASES ASSOCIATED WITH HYALURONAN SYNTHASES EXPRESSION AND CHANGE OF MOLECULAR WEIGHT OF HYALURONAN IN THE JOINT FLUID

โœ Scribed by M. Uzuki; Y. Sasaki; S. Tokunaga; A. Kamataki; K. Nomi; H. Kitagawa; J. Kaiyama; T. Sawai

Book ID
114351069
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
140 KB
Volume
16
Category
Article
ISSN
1063-4584

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## Abstract Hyaluronan or hyaluronic acid (HA) has been used to treat osteoarthritic knees for more than 30 years. Here, we tested the hypothesis that HA with high molecular weight (MW) would have greater effects than HA with low MW on the expression of the plasminogen activator (PA)/plasmin system